The most frequent cause of dementia, Alzheimer's disease (AD) is a neurological condition with an unknown source and pathophysiology that mostly affects older persons.

Neuroimaging- The examination of patients with suspected neurological disorders should include brain imaging, particularly with magnetic resonance imaging (MRI).

In individuals with a sudden start of cognitive impairment and/or fast neurologic deterioration, neuroimaging with a head computed tomography (CT) or MRI scan is categorically needed. Additionally, neuroimaging is advised if physical examination results or medical history point to subdural hematoma, thrombotic stroke, cerebral hemorrhage, or any another structural lesion.

Preferred Modality
Cerebral atrophy– Brain atrophy is a typical symptom of neurodegenerative dementia patients as well as normal aging. Both general and regional atrophy are possible.